An anti-androgen sometimes used off-label for female pattern hair loss under specialist care.
Bicalutamide blocks androgen receptor signalling and has been explored as an off-label option for female pattern hair loss, particularly when other anti-androgens are unsuitable or ineffective. It is not a casual supplement and is not a standard first-line treatment. Potential concerns include liver enzyme changes and pregnancy-related risks, so it requires medical selection, contraception counselling where relevant and monitoring. It should be discussed as a specialist anti-androgen option, not as a universal hair loss treatment.
Ramos et al., Female-pattern hair loss therapeutic update, An Bras Dermatol 2023: https://doi.org/10.1016/j.abd.2022.09.006 ; Valdez-Zertuche & Tosti, 2025 comprehensive alopecia drug review
